When Stacy insists her husband Mark get tests, House insists he can handle things. But despite the fact Mark's tests prove negative, his steadily growing symptoms indicate he is dying. While House struggles with the mystery and makes increasing demands on

House's ex-girlfriend Stacy Warner returns, not for House, but to get help for her ailing husband. While House decides whether or not to take her case, Cuddy forces him to present a lecture to a class of medical students. As he weaves the stories of three

House apparently triggers a stroke in a clinic patient, but the major topic of discussion is House's imminent date with Cameron, The team must deal with the patient's odd lifestyle, overbearing "friend," and reluctant parents in order to stop the strokes

During an meningitis outbreak which overwhelms the clinic, House is drawn to a single patient: a 12-year-old whose symptoms don’t quite match everyone else’s. House, Foreman, and Chase must devise ingenious ways and locations to treat the girlâ

While House and his team scramble to discover what's causing brain and kidney dysfunction in a pregnant woman, Vogler is working to get House fired after House's pharmaeutical speech. House determines the illness, but the woman and her husband must strugg

At a high-level campaign fundraiser, a senator becomes violently ill. Vogler forces House to take the senator's case and offers to let off the hook on firing a team member if he'll deliver a speech on behalf of Vogler's pharmaceutical company. It looks li

House must fire one of his doctors and leaves them to think about it while they deal with an overweight 10-year old child who suffered a heart attack as the result of taking diet pills. House is also faced with a woman who won't accept surgery for a 30 lb

Just before mobster Joey Arnello spills the beans in federal court and enters witness protection, he collapses. Is he faking? A court order instructs House to find out, and fast. House and his team struggle to diagnose and cure Joey while Joey's brother B

Billionaire entrepreneur Edward Vogler spends 100 million on the clinic and becomes the new Chairman of the Board. As a businessman, Vogler intends to turn the clinic into a profitable venue for his biotech venture and plans to eliminate the financially d

A 12-year-old named Gabe (Daryl Sabara) is taken to the hospital after collapses with a rash on his arm. Jeffrey, his father, suggests leishmaniasis and filariasis, but his opinion is dismissed. The team treats Gabe for different conditions including anth

A severely broken arm reveals a bizarre case of bone loss and ends the comeback plans of major league pitcher Hank Wiggen. House suspects Hank, with a history of drug abuse, is lying about using steroids, as his condition worsens. When Hank's kidneys star

While trying to figure out why a young patient won't stop bleeding after a car wreck, House takes Cuddy's challenge and goes off Vicodin for a week in exchange for no clinic duty for a month. If House and his team can't determine the source of his patient

Dr. Foreman believes an uncooperative homeless woman is faking seizures to get a meal ticket at the teaching hospital. But her homelessness strikes a personal chord with Dr. Wilson and he grows determined to keep her from falling between the cracks. Her w

Legendary jazz musician John Henry Giles is checked into the hospital and when he's told he's dying from ALS, he signs a DNR to avoid a slow death. House disagrees with the diagnosis and goes against everyone's wishes when he violates the DNR to save Gile

A toxin sends a high school boy into convulsions, but after an experimental treatment fails and a thorough inspection of the boy's home turns up nothing, the boy's mother refuses to take anymore risks until she's heard from the Center for Disease Control.

Two men are out jogging -- one of them returns back to his wife and discovers her dead asleep and brings her to the clinic. The doctors are puzzled by her symptoms. They consider everything from tumors to breast cancer to rabbit fever. When all the treatm

Dr. House is intrigued by the symptoms of a schizophrenic woman, who displays mixed symptoms, including a tumor, but soon realizes the source of her problems isn't the obvious. House confronts his birthday and Chase confronts his past when the mother's so

A nun whose hands are red, swollen and cracked is sent to House. The nun believes it is stigmata, but House suspects an allergic reaction. He gives her some pills, which cause her to become unable to breathe. As her condition worsens, her fellow sisters p

When a virus is spreading among the hospital, infecting six babies, House and his team must make decisions that could compromise the lives of the babies.

A college student collapses after rowdy sex with his girlfriend. While House and his team attempt to determine the cause, the student's condition continues to deteriorate and his symptoms multiply complicating the diagnosis.

A 16-year old high school student, Dan, starts suffering from nightmares and frequent hallucinations, and he reveals he was hit in the head while playing lacrosse at school. Dan is apparently suffering from MS, and risky brain surgery is needed. Meanwhile

A young kindergarten teacher, Rebecca Adler, who suffers from seizures collapses in her classroom after uncontrolled gibberish slips out her mouth while she is about to teach her students. She is taken to Dr. House and his team of experts who identify it