Patrick Jane and Kristina's first date is interrupted by a report of Red John striking again, which is discovered to be a copycat. But when Kristina reaches out to the real Red John, both she and Jane find themselves in grave danger.

Romantic sparks begin to fly when Patrick Jane and supposed psychic Kristina Frye cross paths again during the CBI investigation into the murder of a charismatic head of a non-profit organization that fights human trafficking.

Patrick Jane and the CBI team investigate the death of a mathematical genius by a gun-wielding clown.

When a media mogul is murdered, Patrick Jane and the CBI team investigate cult leader Bret Stiles, who may have had an axe to grind following the publication of a critical story about his group.

When Patrick Jane's sneaky conduct causes the case of a confessed hitman to be tossed out of court, his annoyed CBI team must start the investigation over from scratch.

When a "Jane Doe" with amnesia and covered in blood steps in front of Cho and Van Pelt's car, Patrick Jane must use all of his skills to discover who she is, her last location and why she lost her memory

Patrick Jane, Lisbon and the CBI team brace themselves to finally meet their new boss, Special Agent Madeleine Hightower.

When Dr. Alicia Seberg, a government research scientist, is exposed to a deadly toxin while at work and has only hours to live, she calls Patrick Jane and the CBI to find her murderer.

Jane and the team are asked to investigate the murder of Gabriel Barge, a prominent chef.

Jane insists on going along when Cho is asked to help with the investigation into the low-profile murder of a former fellow gang member.

When the body of Liselle Douglas, a beautiful, young car salesman, is found stuffed in the trunk of a high-end vehicle at an elite car dealership, Jane and the CBI are asked to investigate.

The CBI is assigned to investigate the murder of someone close to the mayor. Two of the team members have a surprise announcement for everyone.

The CBI investigate the murder of a couple on their way to his high school reunion.

The CBI team investigate the murder of a former professional baseball player, who has started his own baseball talent scouting and training facility for young up-and-coming baseball talents. During the investigation, Jane is knocked out by a baseball and flashes back to his past as a stage performer.

Jane and the CBI investigate the murder of a wealthy jeweler who was killed during a jewel heist at a charity event, however, the investigation takes an interesting turn for the worse when the prime suspect is found dead.

When a violent and shocking crime is committed within the offices of the CBI, Jane and the team are forced to investigate despite fear of who may be behind it. Meanwhile, Rigsby and Van Pelt continue to grow closer.

When the CBI are called in to investigate the kidnapping of a wealthy California heiress, Bosco's strong animosity towards Jane's unconventional methods threatens to cost the young kidnapping victim her life.

After Bosco arrests Jane and puts him in prison for spying on him and his unit as they try to investigate the Red John case, he manages to help Lisbon and the CBI team solve the murder of a young man, even from behind bars.

Jane and the CBI encounter a ghost and a haunted mansion when they investigate the mysterious death of a wealthy man who witnesses say was murdered by a ghost haunting his mansion.

Jane, Lisbon and the entire CBI investigate the murder of a powerful and under-handed criminal attorney whose primary client is one of California's most notorious motorcycle gangs.

In order to prove Lisbon's innocence after she is accused of murdering an infamous pedophile she arrested who was recently released on parole, Jane and the CBI team decide to conduct their own investigation.

Lisbon and the CBI are called in to investigate the death of a prominent State Senator's murdered intern. Meanwhile, Jane attempts to figure out what new information Sam Bosco and his unit have discovered on the Red John case.

The CBI investigates the murder of a woman who is found suffocated after being accused of stealing a million dollars from her employer. Meanwhile, Jane and Lisbon can only watch as the investigation into the Red John case is taken away from them and handed over to CBI Agent Sam Bosco.